The bacteriologist and virologist Thomas Milton Rivers spent over thirty years at the Rockefeller Institute as a researcher in the Department of Bacteriology and from 1937-1955, as Director. Working on measles and pneumonia, Rivers discovered the parainfluenzae bacillus and cultivated vaccine virus for human use, and during the 1950s, he played an important role in coordinating research on poliomyelitis as head of the National Institute for Infantile Paralysis. During the Second World War, Rivers led the Naval Medical Research Unit in the South Pacific, rising to the rank of Rear Admiral. The Rivers Papers contains correspondence, laboratory notes, speeches, and photographs documenting Rivers' activities at the Rockefeller Institute, the development of polio vaccine, and Rivers' Navy experience in the Pacific during World War II.

A pioneer biochemist, Carl Neuberg (1877-1956) spent over thirty years of his productive career as a professor at the University of Berlin (1903-1937) and as Director of the Kaiser Wilhelm Institutes of Biochemistry and Experimental Therapy. His varied research interests resulted in important contributions to the understanding of fermentation processes, solubility and transport phenomena in cells, the chemistry of carbohydrates, sugars, enzymes, and amino acids, and photochemistry. Neuberg was forced out of his position after the Nazi rise to power, and taking refuge in the United States. For the last several years of his life, he worked at New York University. The Neuberg collection consists of correspondence, lab notebooks, documents, photographs, and reprints, nearly all dating from after Neuberg's departure from Germany in 1940. The correspondence documents Neuberg's late-career work and the contacts he developed with American chemical manufacturers and industries involved in fermentation, as well as the burgeoning post-war relationship between scientific research and the federal dollar. Files for the American Cancer Society, U.S. Atomic Energy Commission, and the U.S. Public Health Service in particular contain useful information for study of the politics and mechanics of government grants.

A gifted mathematician, Polish-born Stanislaw Ulam made contributions to set theory, topology, mathematical logic, and number theory, but is most widely remembered for his work in fostering the technical development of thermonuclear weapons. He was associated with Los Alamos Scientific Laboratories for most of the years between 1943 and 1965, and thereafter with the University of Colorado. These papers include personal and professional correspondence, manuscripts of both published and unpublished works, and memorabilia.

Frederick Henry Osborn was an administrator, humanist, and scientist. This collection includes letters, diaries, reports, speeches, drafts of articles and books, oral history interviews, and photographs. There are diaries and letters for his service in Europe with the American Red Cross during World War I. There are some letters and documents, such as patent applications and plans for inventions, from his "business career" period prior to 1928, after which he became a research associate at the American Museum of Natural History studying anthropology and population. This study led to his later important contributions to the redirection of eugenics study in the U.S. and the reorganization of the American Eugenics Society. His other related organizational work and publications relating to human and population genetics are also documented in this collection. There is significant material (letters, diaries, reports) related to Osborn's World War II contributions as the chairman of the Civilian Committee on Selective Service in 1940, and as head of the Morale Branch of the U.S. Army (later, the Information and Education Division of Special Services) in 1941. Also included are important documents, especially his diary, from his work as deputy representative on the U.S. Atomic Energy Commission and the U.N. Commission for Conventional Armaments. His letters, writings, and speeches relating to foreign policy are extensive, spanning the period from the 1940s until his death, much of it from the Vietnam War years. The correspondence with Kathleen Harris is particularly rich in this respect. There is family correspondence reflecting his dynamic philosophy of life, with long series of letters to his parents (1917-1945) and to his children and grandchildren. His later civic and regional interests, as a long-time resident of Garrison, N.Y., are evidenced in the work he did on the Palisades Interstate Park Commission.

Though the Miscellaneous Manuscripts collection is composed of items that do not fall readily into any other existing collection, the two dominant intellectual areas represented in the collection are Early American History and History of Science.

The Anthony F. C. Wallace Papers include correspondence to and from 20th century anthropologists, ethnologists, historians, linguists, and psychiatrists and provides a wealth of resources for the study of technological and social change, American Indians, culture and personality, revitalization movements, the anthropological study of religion, and the cultural and biological bases of behavior. In addition to Wallace's correspondence, research notes, and drafts, the collection includes Wallace family correspondence and photographs, as well as Wallace's writings from childhood through recent years.

For many years referred to as the "Franz Boas Collection of American Indian Linguistics," this collection consists of a large body of linguistic and ethnographic material gathered together by Boas and many of his colleagues and students primarily from the 1890s to the 1940s. It contains the bulk of Boas's own fieldwork material, with the main exception of most of his Inuit and earliest Northwest Coast fieldwork. It contains the majority of the work sponsored by American Council of Learned Societies Committee on Native American Languages, which was directed by Franz Boas, Edward Sapir, Alfred Kroeber, and other academic linguists from 1927-1937. The collection, however, also contains related kinds of fieldwork and derived secondary materials created outside the auspices of this Committee, both earlier and later. The first deposit of the material arrivied in 1945. Subsequently, additional related materials were donated and added, as noted in the listings. Additionally, the documentary materials produced by some of the early projects (1945 to circa 1955) of the APS Phillips Fund for Native American Research were added to this collection. The collection has grown to over 80 linear feet of material representing at least 166 languages and dialects from the United States, Canada, and Mexico. The formats range from field notes and ethnographic texts to slip files, vocabularies, lexica, and grammars, and dozens of linguists and Native consultants are represented.

One of the seminal figures in the emergence of the Modern or Neo-Darwinian Synthesis during the mid-twentieth century, George Gaylord Simpson (1902-1984) helped define the unique contribution made by vertebrate paleontology to the life sciences. A specialist in Mesozoic and early Cenozoic mammals, Simpson's contributions to the fusion of Darwinian natural selection and Mendelian genetics were both empirical and theoretical, culminating in his major works Tempo and Mode in Evolution and The Meaning of Evolution. From his posts at the American Museum of Natural History (1927-1959), Columbia University (1945-1959), Harvard (1959-1967), and the University of Arizona (1967-1984), Simpson became one of the most influential paleontologists of the century, helped in part by his ability to write successfully for both a technical, professional audience and a popular audience. The Simpson Papers include a comprehensive assemblage of professional and personal correspondence, reflecting nealy all phases of Simpson's career. Written with charm, wit, and a sense of literary style, the correspondence touches on all aspects of modern paleontology, providing an important perspective on the emergence of contemporary evolutionary theory, biogeography, systematic theory and methodology, the relationship of science and religion, and creationism, as well as more general issues in scientific epistemology and social and political issues. The collection also includes autobiographical data and writings, lectures, class notes and papers, research data, material on his scientific expeditions (diaries in carbon form, photos, notes, etc.), publication material (he was author of some 800 publications), extensive photographic material, diplomas, and medals.